So here is the list so far of particular items I think whose drop rate should increase with the main purpose being to get players t advance at a certain pace. Note that this will of course be a work in progress.

Regarding runes
Increase in general (and yes I do mean in general) but very slightly the drop rates for all runes, but with everything below mal being the most and everything after ohm being the least. The new "middle runes" (mal through ohm) ought to help newer players advance more if the drop rate for such is better than it is now. Perhaps such should be increased in uber or omega areas.

Regarding blue organs
I know these aren't too find to hard, but perhaps the drop rate for such ought to be tweaked a little more higher (certainly something to be considered if everything else is ignored).

To be continued/edited